Show simple item record

dc.contributor.author Jardim, Guilherme Augusto de Melo
dc.contributor.author Cruz, Eduardo Henrique Guimarães da
dc.contributor.author Valença, Wagner
dc.contributor.author Resende, Jarbas Magalhães
dc.contributor.author Rodrigues, Bernardo Lages
dc.contributor.author Soares, Daniela Fernandes Ramos
dc.contributor.author Oliveira, Ronaldo
dc.contributor.author Silva, Pedro Eduardo Almeida da
dc.contributor.author Silva Júnior, Eufrânio Nunes da
dc.date.accessioned 2017-04-27T22:06:09Z
dc.date.available 2017-04-27T22:06:09Z
dc.date.issued 2015
dc.identifier.citation JARDIM, Guilherme Augusto de Melo et al. On the search for potential antimycobacterial drugs: Synthesis of naphthoquinoidal, phenazinic and 1,2,3-triazolic compounds and evaluation against Mycobacterium tuberculosis. Journal of the Brazilian Chemical Society, v. 26, n. 5, p. 1-15, 2015. Disponível em: < http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532015000501013&lng=en&nrm=iso&tlng=en#c01>. Acesso em: 08 abr. 2017. pt_BR
dc.identifier.issn 0103-5053
dc.identifier.uri http://repositorio.furg.br/handle/1/7149
dc.description.abstract Fifteen naphthoquinones, sixteen phenazines and fifteen aryl triazoles were synthesized and evaluated against Mycobacterium tuberculosis. Twenty five substances are reported here for the first time and, among all of the compounds evaluated, six presented MIC (minimal inhibitory concentration) values ≤ 6.25 μg mL-1. These substances are promising antimycobacterial prototypes. pt_BR
dc.language.iso eng pt_BR
dc.rights open access pt_BR
dc.subject Lapachol pt_BR
dc.subject Phenazines pt_BR
dc.subject Mycobacterium tuberculosis pt_BR
dc.subject Antitubercular pt_BR
dc.subject Triazoles pt_BR
dc.title On the search for potential antimycobacterial drugs: synthesis of naphthoquinoidal, phenazinic and 1,2,3-triazolic compounds and evaluation against Mycobacterium tuberculosis pt_BR
dc.type article pt_BR
dc.identifier.doi http://dx.doi.org/10.5935/0103-5053.20150067 pt_BR


Files in this item

0103-5053-jbchs-26-05-1013.pdf
Size: 750.1Kb Format: PDF

This item appears in the following Collection(s)

:

  • FAMED – Artigos publicados em periódicos

    • Show simple item record