-
-
Spies, Fernanda Sá; Groll, Andrea Von; Ribeiro, Andrezza Wolowski; Soares, Daniela Fernandes Ramos; Ribeiro, Marta Osório; Costa, Elis Regina Dalla; Martin, Anandi; Palomino, Juan Carlos; Rossetti, Maria Lucia; Zaha, Arnaldo; Silva, Pedro Eduardo Almeida da
(2012)
When bacteria develop drug-resistant mutations, there is often an associated biological cost; however,
some strains can exhibit low- or no-cost mutations. In the present study, a quantitative resazurin
reduction assay ...
-
-
Perizzolo, Paulo Fernando; Dalla Costa, Elis Regina; Ribeiro, Andrezza Wolowski; Spies, Fernanda Sá; Ribeiro, Marta Osório; Dias, Claudio Renato Rodrigues; Unis, Gisela; Silva, Pedro Eduardo Almeida da; Gomes, Harrison Magdinier; Suffys, Philip Noel; Rossetti, Maria Lucia Rosa
(2012)
A major threat to tuberculosis (TB) control programs is the emergence of drug resistant Mycobacterium tuberculosis strains that cause TB that cannot be cured by standard anti-TB drug regimens. Because few data exist on ...
-
-
Costa, Elis Regina Dalla; Ribeiro, Marta Osório; Silva, Márcia Susana Nunes; Arnold, Liane Silveira; Rostirolla, Diana Carolina; Cafrune, Patricia Izquierdo; Espinoza, Roger Ivan Calderon; Palaci, Moises; Telles, Maria Alice da Silva; Ritacco, Viviana; Suffys, Philip Noel; Lopes, Maria Luiza; Campelo, Creusa Lima; Miranda, Silvana Spíndola de; Kremer, Kristin; Silva, Pedro Eduardo Almeida da; Fonseca, Leila de Souza; Ho, John L; Kritski, Afrânio Lineu; Rossetti, Maria Lucia Rosa
(2009)
Background: Mutations associated with resistance to rifampin or streptomycin have been reported for W/Beijing and Latin American Mediterranean (LAM) strain families of Mycobacterium tuberculosis. A few studies with limited ...
-
-
Gautério, Daiane Porto; Ribeiro, Marta Osório; Groll, Andrea Von; Silva, Márcia; Soares, Daniela Fernandes Ramos; Rossetti, Maria Lucia Rosa; Scaini, Carlos James; Silva, Pedro Eduardo Almeida da
(2008)
Triclosan é um biocida amplamente utilizado na comunidade e nos hospitais. Um dos alvos do triclosan é uma enoil-redutase que está presente no Mycobacterium tuberculosis, sendo também o principal alvo da isoniazida (INH), ...
-
-
Spies, Fernanda Sá; Ribeiro, Andrezza Wolowski; Soares, Daniela Fernandes Ramos; Ribeiro, Marta Osório; Martin, Anandi; Palomino, Juan Carlos; Rossetti, Maria Lucia Rosa; Silva, Pedro Eduardo Almeida da; Zaha, Arnaldo
(2011)
Mutations related to streptomycin resistance in the rpsL and rrs genes are well known and can explain about 70% of this phenotypic resistance. Recently, the gidB gene was found to be associated with low-level streptomycin ...
-
-
Honscha, Gunther; Groll, Andrea Von; Valença, Mariana Soares; Soares, Daniela Fernandes Ramos; Sanchotene, Karine Ortiz; Scaini, Carlos James; Ribeiro, Marta Osório; Silva, Pedro Eduardo Almeida da
(2008)
OBJECTIVES: To evaluate the performance of laboratory diagnosis of tuberculosis, clinical samples underwent culture, species identification and drug susceptibility testing (DST). METHODS: A total of 554 samples from 269 ...
-
-
Honscha, Gunther; Groll, Andrea Von; Valença, Mariana Soares; Soares, Daniela Fernandes Ramos; Sanchotene, Karine Ortiz; Scaini, Carlos James; Ribeiro, Marta Osório; Silva, Pedro Eduardo Almeida da
(2008)
OBJECTIVES: To evaluate the performance of laboratory diagnosis of tuberculosis, clinical samples underwent culture, species identification and drug susceptibility testing (DST). METHODS: A total of 554 samples from 269 ...
-
-
Boffo, Maria Marta Santos; Mattos, Ivo Gomes de; Ribeiro, Marta Osório; Oliveira Netto, Isabel Cristina de
(2004)
Introdução: A sinergia entre a tuberculose e o vírus da imunodeficiência humana é responsável pelo aumento da morbi-mortalidade dos pacientes com AIDS.Objetivo: Delinear o perfil de pacientes com tuberculose e AIDS na ...
