The development of diagnostic tests which can readily differentiate between vaccinated and tuberculosis-infected individuals is crucial for the wider utilization of bacillus Calmette-Guérin (BCG) as vaccine in humans and ...

Introduction: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric pathology that has an important prevalence among young people and is difficult to diagnose. It is usually treated with methylphenidate, ...

During the austral winter the appearance of the Magellanic penguin (Spheniscus magellanicus) is common on the southern coast of Brazil. The oil pollution constitutes a major cause of death of these birds. The monitoring of ...

Memory persistence in the inhibitory avoidance (IA) task has been recently shown to require a new event of consolidation 12 hr after acquisition. The immobilization stress (IS) model is largely used to study the effects ...

Cholinergic dysfunction has been associated with cognitive abnormalities in a variety of neurodegenerative and neuropsychiatric diseases. Here we tested how information processing is regulated by cholinergic tone in ...

Carbon nanotubes (CNT) are promising materials for biomedical applications, especially in the field of neuroscience; therefore, it is essential to evaluate the neurotoxicity of these nanomaterials. The present work assessed ...

Mycobacterium bovis is the main causative agent of animal tuberculosis (TB) and it may cause TB in humans. Molecular typing of M. bovis isolates provides precise epidemiological data on issues of inter- or intra-herd ...

Background: Blooms of the saxitoxin-producing cyanobacterium Cylindrospermopsis raciborskii have been contaminating drinking water reservoirs in Brazil for many years. Although acute effects of saxitoxin intoxication are ...

A criptococose é uma micose primariamente pulmonar, sendo adquirida por meio de inalação de propágulos fúngicos infectantes encontrados no ambiente. Um dos principais agentes etiológicos da criptococose é a espécie ...

Purpose This study evaluates the advantage of the quercetin encapsulation in nanosized emulsion (QU-NE) administered orally in rats in order to demonstrate its anti-oedematous and antioxidant effects as well as its ...

As plantas medicinais constituíram durante séculos a base da medicina tradicional, fundamentada nos conhecimentos empíricos de diferentes culturas, passadas entre gerações. A partir de plantas ou derivados vegetais são ...

The mainstay of treatment for acute bronchiolitis remains supportive care. The objective of this study was to assess the efficacy and safety of nebulized hypertonic saline (HS) in infants with acute bronchiolitis.

High speed countercurrent chromatography (HSCCC) was used to isolate the dammarane type triterpene shoreic acid from the dichloromethane extract of leaves of Cabralea canjerana, which showed activity against Mycobacterium ...

Anthelmintics used for intestinal helminthiasis treatment are generally effective; however, their effectiveness in tissue parasitosis (i.e. visceral toxocariasis) is moderate. The aim of this study was to evaluate the in ...

Os agrotóxicos são amplamente utilizados no meio rural e sua larga utilização desprovida de medidas de biossegurança apropriadas, vem provocando impactos potenciais tanto para o ambiente quanto para a saúde humana. Os ...

Fifteen naphthoquinones, sixteen phenazines and fifteen aryl triazoles were synthesized and evaluated against Mycobacterium tuberculosis. Twenty five substances are reported here for the first time and, among all of the ...

Tuberculosis remains a serious public health problem, with nine million cases being reported annually. Treatment with antibiotics is the most effective mechanism to control this disease, although the increase in cases ...

JUSTIFICATIVA E OBJETIVO: A Ilex paraguariensis St. Hilaire é conhecida popularmente como mate ou erva-mate, consumida popularmente no sul do Brasil, Paraguai e Argentina. Estudos têm evidenciado atividades bioativas da ...

Paracoccidioidomycosis (PCM) is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis and is endemic to Brazil. The aim of this study was to perform a retrospective analysis of the PCM cases in the ...

A tuberculose (TB) é uma doença infecciosa com uma incidência mundial estimada de 8,8 milhões de casos. Considerando o aumento no número de casos por cepas multidrogarresistente (MDR-TB) e o reduzido arsenal terapêutico, ...