Show simple item record Madrid, Isabel Martins Xavier, Melissa Orzechowski Mattei, Antonella Souza Fernandes, Cristina Gevehr Guim, Thomas Normanton Santin, Rosema Schuch, Luiz Filipe Damé Nobre, Márcia de Oliveira Meireles, Mario Carlos Araujo 2012-10-15T11:59:24Z 2012-10-15T11:59:24Z 2010
dc.identifier.citation MADRID, Isabel Martins et al. Role of melanin in the pathogenesis of cutaneous sporotrichosis. Microbes and Infection, v. 12, n. 2, p. 162-165, 2010. Disponível em: <>. Acesso em: 08 out. 2012. pt_BR
dc.identifier.issn 1286-4579
dc.description.abstract In this study, we evaluate the clinical, histopathological and ultra structural aspects of the infection by field strain (MELþ) and mutated strain (MEL ) of Sporothrix schenckii. The development of sporotrichosis at the inoculation sites was similar for both groups of animals after the second week of the experimental period. Statistical differences appeared only at weeks 3 and 5. The pigmented isolate had greater tissue invasive capacity, promoting the formation of multifocal granulomas, whereas the albino isolate induced an enhanced inflammatory response, restraining the agent to the core of the granulomas. pt_BR
dc.language.iso eng pt_BR
dc.rights restrict access pt_BR
dc.subject Sporothrix schenckii pt_BR
dc.subject Melanin pt_BR
dc.subject Virulence factors pt_BR
dc.title Role of melanin in the pathogenesis of cutaneous sporotrichosis pt_BR
dc.type article pt_BR

Files in this item

This item appears in the following Collection(s)


  • FAMED – Artigos publicados em periódicos
  • Show simple item record