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dc.contributor.author Carneiro, Paula Fernandes
dc.contributor.author Pinto, Maria do Carmo Freire Ribeiro
dc.contributor.author Coelho, Tatiane Silveira
dc.contributor.author Cavalcanti, Bruno Coêlho
dc.contributor.author Pessoa, Cláudia
dc.contributor.author Simone, Carlos Alberto de
dc.contributor.author Nunes, Isabelle Karine da Costa
dc.contributor.author Oliveira, Nathália Milanez de
dc.contributor.author Almeida, Renata Gomes de
dc.contributor.author Pinto, Antonio Ventura
dc.contributor.author Moura, Kelly Cristina Gallan de
dc.contributor.author Pedro, Eduardo Almeida da
dc.contributor.author Silva Júnior, Eufrânio Nunes da
dc.date.accessioned 2013-08-08T21:21:53Z
dc.date.available 2013-08-08T21:21:53Z
dc.date.issued 2011
dc.identifier.citation CARNEIRO, Paula Fernandes et al. Quinonoid and phenazine compounds: synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of mycobacterium tuberculosis. European Journal of Medicinal Chemistry, v. 46, p. 4521-4529, 2011. Disponível em: <http://ac.els-cdn.com/S0223523411005393/1-s2.0-S0223523411005393-main.pdf?_tid=9fd972c2-ffaf-11e1-b57d-00000aab0f01&acdnat=1347766736_c085ec795ff62b4b05de2d8ce3ee57da>. Acesso em: 16 set. 2012. pt_BR
dc.identifier.issn 0223-5234
dc.identifier.uri http://repositorio.furg.br/handle/1/3666
dc.description.abstract Several quinonoid and phenazine compounds were synthesized in moderate to high yields and showed activity against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis. The cytotoxity of the compounds were evaluated against human peripheral blood mononuclear cells (PBMC) and these substances emerge as promising antitubercular prototypes. pt_BR
dc.language.iso eng pt_BR
dc.rights restrict access pt_BR
dc.subject Lapachol pt_BR
dc.subject Phenazines pt_BR
dc.subject Mycobacterium tuberculosis pt_BR
dc.subject Antitubercular pt_BR
dc.title Quinonoid and phenazine compounds: synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of mycobacterium tuberculosis pt_BR
dc.type article pt_BR
dc.identifier.doi 10.1016/j.ejmech.2011.07.026 pt_BR


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