dc.contributor.author |
Lopes, Neusa Helena |
|
dc.contributor.author |
Paulitsch, Felipe da Silva |
|
dc.contributor.author |
Pereira, Alexandre da Costa |
|
dc.contributor.author |
Góis, Aécio Flávio Teixeira de |
|
dc.contributor.author |
Gagliardi, Antonio Ricardo de Toledo |
|
dc.contributor.author |
Garzillo, Cibele Larrosa |
|
dc.contributor.author |
Ferreira, João Francisco |
|
dc.contributor.author |
Stolf, Noedir Antônio Groppo |
|
dc.contributor.author |
Hueb, Whady Armindo |
|
dc.date.accessioned |
2013-09-23T20:30:58Z |
|
dc.date.available |
2013-09-23T20:30:58Z |
|
dc.date.issued |
2008 |
|
dc.identifier.citation |
LOPES, Neusa Helena et al. Impact of metabolic syndrome on the outcome of patients with stable coronary artery disease: 2-year follow-up of the MASS II study. Pathophysiology And Natural History, São Paulo, v. 6, n. 19, p.383-389, 2008. Disponível em: <http://www.ncbi.nlm.nih.gov/pubmed/18955830>. Acesso em: 30 ago. 2012. |
pt_BR |
dc.identifier.uri |
http://repositorio.furg.br/handle/1/3844 |
|
dc.description.abstract |
Objective We characterized the impact of the metabolic syndrome (MetS) and its components on cardiovascular adverse events in patients with symptomatic chronic multivessel coronary artery disease, which have been
followed prospectively for 2 years.
Methods Patients enrolled in the MASS II study were evaluated for each component of the MetS, as well as the full syndrome.
Results The criteria for MetS were fulfilled in 52% of patients. The presence of MetS (P < 0.05), glucose intolerance (P = 0.007), and diabetes (P = 0.04) was associated with an increased mortality in our studied
population. Moreover, despite a clear tendency for each of its components to increase the mortality risk, only
the presence of the MetS significantly increased the risk of mortality among nondiabetic study participants
in a multivariate model (P = 0.03, relative risk 3.5, 95% confidence interval 1.1–6). Finally, MetS was still associated with increased mortality even after adjustment for diabetes status. These results indicate a strong and consistent relationship of the MetS with mortality in patients with stable coronary artery disease. Conclusion Although glucose homeostasis seems to be
the major force driving the increased risk of MetS, the operational diagnosis of MetS still has information for stratifying patients when diabetes information is taken into account. |
pt_BR |
dc.language.iso |
eng |
pt_BR |
dc.rights |
restrict access |
pt_BR |
dc.subject |
Coronary disease |
pt_BR |
dc.subject |
Metabolic syndrome |
pt_BR |
dc.subject |
Prognosis |
pt_BR |
dc.subject |
Risk factor |
pt_BR |
dc.title |
Impact of metabolic syndrome on the outcome of patients with stable coronary artery disease: 2-year follow-up of the MASS II study |
pt_BR |
dc.type |
article |
pt_BR |