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Alves-Costa, Fernanda Antunes; Figueiredo, Marcio de Azevedo; Lanes, Carlos Frederico Ceccon; Almeida, Daniela Volcan; Marins, Luis Fernando Fernandes; Wasko, Adriane Pinto
(2012)
The presence of higher level of exogenous growth hormone (GH) in transgenic animals could lead to several physiological alterations. A GH transgenic zebrafish (Danio rerio) line was compared to nontransgenic (NT) samples ...
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Rosa, Carlos Eduardo da; Figueiredo, Marcio de Azevedo; Lanes, Carlos Frederico Ceccon; Almeida, Daniela Volcan; Marins, Luis Fernando Fernandes
(2011)
The aim of this study was to evaluate the
effects of growth hormone (GH)overexpression on the gene expression profile of multiple components of the antioxidant defense system(ADS)of different genotypes of a GH transgenic ...
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Kuradomi, Rafael Yutaka; Figueiredo, Márcio de Azevedo; Lanes, Carlos Frederico Ceccon; Rosa, Carlos Eduardo da; Almeida, Daniela Volcan; Maggioni, Rodrigo; Silva, Maeli Dal Pai; Marins, Luis Fernando Fernandes
(2011)
The aim of the present study was to
analyse the morphology of white skeletal muscle in males and females from the GH-transgenic zebrafish(Danio rerio) lineage F0104, comparing the expression of genes related to the ...
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Fonseca, Duane Barros da; Rosa, Carlos Eduardo da; Kuradomi, Rafael Yutaka; Almeida, Daniela Volcan; Lanes, Carlos Frederico Ceccon; Figueiredo, Marcio de Azevedo; Dytz, Aline Guerra; Marins, Luis Fernando Fernandes
(2010)
Growth hormone (GH) excess causes an increment in the metabolic rate and in reactive oxygen species generation, which accelerate the ageing process in mammals. Considering that there is no information on this subject in ...
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Figueiredo, Marcio de Azevedo; Lanes, Carlos Frederico Ceccon; Almeida, Daniela Volcan; Marins, Luis Fernando Fernandes
(2007)
In fish, microinjection is the method most frequently used for gene transfer. However, due to delayed transgene integration this technique almost invariably produces mosaic individuals and if the gene is not integrated ...
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Almeida, Daniela Volcan; Nornberg, Bruna Félix da Silva; Monserrat, Laura Alicia Geracitano; Barros, Daniela Marti; Monserrat, José María; Marins, Luis Fernando Fernandes
(2009)
We have evaluated the homology of the electrophile-responsive element (EpRE) core sequence, a binding site for the Nrf2 transcription factor, in the proximal promoters of the mouse and zebrafish glutathione-S-transferase ...
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Almeida, Daniela Volcan; Trindade, Gilma Santos; Monserrat, Laura Alicia Geracitano; Barros, Daniela Marti; Monserrat, José María; Marins, Luis Fernando Fernandes
(2008)
Induction of many genes encoding detoxifying enzymes and antioxidant proteins is mediated through a common mechanism, which is controlled by electrophile-responsive elements (EpRE)within the regulatory region of those ...
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Rosa, Carlos Eduardo da; Figueiredo, Marcio de Azevedo; Lanes, Carlos Frederico Ceccon; Almeida, Daniela Volcan; Monserrat, José María; Marins, Luis Fernando Fernandes
(2008)
Growth hormone overexpression increases growth and consequently increases the metabolic rate in fishes. Therefore, the objective of this study was to evaluate the
effects of growth hormone overexpression in zebrafish ...
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Martins, Camila De Martinez Gaspar; Almeida, Daniela Volcan; Marins, Luis Fernando Fernandes; Bianchini, Adalto
(2011)
Waterborne Cu effects on the transcription of genes encoding ion-transporting proteins and the activities of these proteins were evaluated in gills of the blue crab Callinectes sapidus acclimated to diluted (2%) and full ...
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Studzinski, Ana Lupe Motta; Almeida, Daniela Volcan; Lanes, Carlos Frederico Ceccon; Figueiredo, Marcio de Azevedo; Marins, Luis Fernando Fernandes
(2009)
Homozygote individuals (HO) of the GH-transgenic zebrafish lineage (F0104), despite expressing double the amount of growth hormone (GH) in relation to the hemizygote (HE) individuals, presented smaller growth in relation ...
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Figueiredo, Marcio de Azevedo; Lanes, Carlos Frederico Ceccon; Almeida, Daniela Volcan; Proietti, Maíra Carneiro; Marins, Luis Fernando Fernandes
(2007)
Most biological actions of growth hormone (GH) are mediated by the insulin-like growth factor I (IGF-I) that is produced after the interaction of the hormone with a specific cell surface receptor, the GH receptor (GHR). ...