Integrated biological responses of zebrafish (Danio rerio) to analyze water quality in regions under anthropogenic influence

Amado, Lílian Lund; Rosa, Carlos Eduardo da; Castro, Micheli Rosa de; Votto, Ana Paula de Souza; Santos, Luciane Cougo dos; Marins, Luis Fernando Fernandes; Trindade, Gilma Santos; Fraga, Diego Severo; Damé, Rita de Cássia Fraga; Barros, Daniela Marti; Monserrat, Laura Alicia Geracitano; Bianchini, Adalto; Torre, Fernando De La; Monserrat, José María


This study analyzed water quality in regions around Patos lagoon (Southern Brazil) that are under anthropogenic pressure. Water samples were collected from five different sites, including one used as a source for human consumption (COR) and others known to be influenced by human activities (IP). Danio rerio Teleostei, Cyprinidae)organisms were exposed for 24 h to these water samples plus a control group.It was observed that: (1) reactive oxygen species levels were lower in COR and IP than in the control group; (2) glutamate-cysteine ligase (catalytic subunit) expression was higher in COR than in other sites;(3) exposure to all water samples affected long-term memory(LTM) when compared to control group.Thus, some water samples possess the ability to modulate the antioxidant system and to induce a decline in cognitive functions, as measured by LTM. The obtained results indicate that a combination of variables of different organization level (molecular, biochemical and behavioral) can be employed to analyze water quality in impacted regions.

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  • ICB - Artigos publicados em periódicos