Show simple item record Valença, Mariana Soares Scaini, João Luis Rheingantz Abilleira, Fernanda de Souza Gonçalves, Carla Vitola Groll, Andrea Von Silva, Pedro Eduardo Almeida da 2017-03-06T13:08:35Z 2017-03-06T13:08:35Z 2015
dc.identifier.citation VALENÇA, Mariana Soares; et al. Prevalence of tuberculosis in prisons: risk factors and molecular epidemiology. The International Journal of Tuberculosis and Lung Disease. v. 19, n. 10, p. 1182-1187, 2015. Disponível em: < >. Acesso em: 13 jan. 2017. pt_BR
dc.description.abstract SETTING: Tuberculosis (TB) in prisons is a challenge for the public health system. Active and passive case screening are important tools for TB case detection. OBJECTIVE: To characterise TB in a southern Brazil prison in terms of epidemiological variables, diagnostic approaches and clinical isolate genotypes. DESIGN: Inmates of a southern Brazilian prison were assessed using active and passive TB case screening. Sputum microscopy, culture, drug susceptibility testing and genotyping were performed. Data were analysed using descriptive statistics and multivariable logistic regression. RESULTS: TB prevalence was 4712 per 100 000 inmates, and was associated with low educational level, time incarcerated, productive cough, previous TB history, smoking and human immunodeficiency virus (HIV) infection. Overall, 27.8% of TB cases were detected by culture only; the prevalence of drug-resistant strains was 7.8%; 58.3% of clinical isolates had an identical genotypic profile. CONCLUSION: The study showed extensive circulation of Mycobacterium tuberculosis strains in a highly endemic prison. It is recommended that priority be given to the evaluation of prison inmates with longer jail times, those who are HIV-positive, those with symptoms and those with a previous history of tuberculosis. We observed that active case finding induced passive case detection. pt_BR
dc.language.iso eng pt_BR
dc.rights open access pt_BR
dc.subject Mycobacterium tuberculosis pt_BR
dc.subject Diagnosis pt_BR
dc.subject Genotyping pt_BR
dc.subject Multidrug resistance pt_BR
dc.subject Prisons pt_BR
dc.title Prevalence of tuberculosis in prisons: risk factors and molecular epidemiology pt_BR
dc.type article pt_BR
dc.identifier.doi pt_BR

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