Browsing FAMED – Faculdade de Medicina by Author "Silva, Pedro Eduardo Almeida da"

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  • Synthesis and antituberculosis activity of new fatty acid amides 

    D'Oca, Caroline Da Ros Montes; Coelho, Tatiane Silveira; Marinho, Tamara Germani; Hack, Carolina Rosa Lopes; Duarte, Rodrigo da Costa; Silva, Pedro Eduardo Almeida da; D'Oca, Marcelo Gonçalves Montes (2010)
    This work reports the synthesis of new fatty acid amides from C16:0, 18:0, 18:1, 18:1 (OH), and 18:2 fatty acids families with cyclic and acyclic amines and demonstrate for the first time the activity of these compounds ...
  • Synthesis and in vitro antimycobacterial activity of 3-substituted 5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-1-(isonicotinoyl) pyrazoles 

    Silva, Pedro Eduardo Almeida da; Soares, Daniela Fernandes Ramos; Bonacorso, Helio Gauze; Iglesia, Agustina de la; Oliveira, Marli Redin; Coelho, Tatiane Silveira; Navarini, Jussara; Morbidoni, Hector; Zanatta, Nilo; Martins, Marcos Antonio Pinto (2008)
    A series of 3-substituted 5-hydroxy-5-trifluoro[chloro]methyl-1H-1-isonicotinoyl-4,5-dihydropyrazoles (2a–i) were synthesised by the cyclocondensation reaction of 4-methoxy-1,1,1-trifluoro[chloro]-4 (substituted)-alk-3-en-2-ones ...
  • The activity of flavones and oleanolic acid from Lippia lacunosa against susceptible and resistant Mycobacterium tuberculosis strains 

    Duarte, Aline Castellar; Coelho, Tatiane Silveira; Silva, Pedro Eduardo Almeida da; Soares, Daniela Fernandes Ramos; Lourenço, Maria Cristina da Silva; Lage, Celso Luiz Salgueiro; Julião, Lisieux de Santana; Barbosa, Ymira Albuquerque Gálico; Leitão, Suzana Guimarães (2011)
    Tuberculosis (TB), caused by Mycobacterium tuberculosis, is the world’s number one killer among infectious diseases. The search for new natural products that can act as drugs against TB has received increased attention ...
  • The BACTEC MGIT™ 320 system as a laboratory tool to diagnose tuberculosis in a brazilian hospital with a high prevalence of HIV infection 

    Brum, Clarice Brinck; Soares, Daniela Fernandes Ramos; Abilleira, Fernanda de Souza; Silva, Ana Bárbara Scholante; Groll, Andrea Von; Silva, Pedro Eduardo Almeida da (2016)
    ABSTRACT Introduction: The World Health Organization endorses the BACTEC Mycobacterial Growth Indicator Tube (MGIT)™ system as a rapid, sensitive, and specifi c method to diagnostic of tuberculosis. Here, we compared the ...
  • The BACTEC MGIT™ 320 system as a laboratory tool to diagnose tuberculosis in a Brazilian hospital with a high prevalence of HIV infection 

    Brum, Clarice Brinck; Soares, Daniela Fernandes Ramos; Abilleira, Fernanda de Souza; Silva, Ana Bárbara Scholante; Groll, Andrea Von; Silva, Pedro Eduardo Almeida da (2016)
    Introduction: The World Health Organization endorses the BACTEC Mycobacterial Growth Indicator Tube (MGIT)™ system as a rapid, sensitive, and specifi c method to diagnostic of tuberculosis. Here, we compared the performance ...
  • The laboratory as a tool to qualify tuberculosis diagnosis 

    Honscha, Gunther; Groll, Andrea Von; Valença, Mariana Soares; Soares, Daniela Fernandes Ramos; Sanchotene, Karine Ortiz; Scaini, Carlos James; Ribeiro, Marta Osório; Silva, Pedro Eduardo Almeida da (2008)
    OBJECTIVES: To evaluate the performance of laboratory diagnosis of tuberculosis, clinical samples underwent culture, species identification and drug susceptibility testing (DST). METHODS: A total of 554 samples from 269 ...
  • The laboratory as a tool to qualify tuberculosis diagnostic 

    Honscha, Gunther; Groll, Andrea Von; Valença, Mariana Soares; Soares, Daniela Fernandes Ramos; Sanchotene, Karine Ortiz; Scaini, Carlos James; Ribeiro, Marta Osório; Silva, Pedro Eduardo Almeida da (2008)
    OBJECTIVES: To evaluate the performance of laboratory diagnosis of tuberculosis, clinical samples underwent culture, species identification and drug susceptibility testing (DST). METHODS: A total of 554 samples from 269 ...
  • The multidrug transporters belonging to major facilitator superfamily (MFS) in mycobacterium tuberculosis 

    Rossi, Edda de; Arrigo, Patrizio; Bellinzoni, Marco; Silva, Pedro Eduardo Almeida da; Martín, Carlos; Aínsa, José; Guglierame, Paola; Riccardi, Giovanna (2002)
    Background: Both intrinsic and acquired multidrug resistance play an important role in the insurgence of tuberculosis. Detailed knowledge of the molecular basis of drug recognition and transport by multidrug transport ...
  • Triterpenes and the Antimycobacterial Activity of Duroia macrophylla Huber (Rubiaceae) 

    Martins, Daiane; Carrion, Lillian Lucas; Soares, Daniela Fernandes Ramos; Salomé, Kahlil Schwanka; Silva, Pedro Eduardo Almeida da; Barison, Andersson; Nunez, Cecilia Veronica (2013)
    Duroia macrophylla popularly known as “cabec¸a-de-urubu,” “apuru ´ ´ı,” or “puru´ı-grande-da-mata” occurs in the Amazon Forest. Its leaves and branches were collected twice and extracted with dichloromethane and methanol. ...