Antioxidant effect of phycocyanin on oxidative stress induced with monosodium glutamate in rats

Bertolin, Telma Elita; Farias, Daniele; Guarienti, Cíntia; Petry, Fernanda Tais Souza; Colla, Luciane Maria; Costa, Jorge Alberto Vieira


The objective of this work was to study the antioxidant effect of phycocyanin on the oxidative stress induced by monosodium glutamate in the rats. The tests were performed with 32 rats of Wistar breed, divided into four groups, which were administered saline solution of phycocyanin, monosodium glutamate and monosodium glutamate plus phycocyanin. Sulfhydryl groups and the secondary substances derived from lipid oxidation were determined through the level of TBA. The evaluation of these values and the level of sulfhydryl showed that the administration of phycocyanin presented significant antioxidant effect (p < 0.05) reducing the oxidative stress induced by the monosodium glutamate in vivo.

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  • EQA - Artigos Publicados em Periódicos