Effect of Microalga Spirulina platensis (Arthrospira platensis) on Hippocampus Lipoperoxidation and Lipid Profile in Rats with Induced Hypercholesterolemia

Bertolin, Telma Elita; Pilatti, Dayane; Giacomini, Ana Cristina Vendrametto Varrone; Bavaresco, Caren Serra; Colla, Luciane Maria; Costa, Jorge Alberto Vieira


Studies have been conducted on microalga Spirulina platensis (Arthrospira platensis) due to its therapeutic potential in several areas, including the capacity for preventing and decreasing the damages caused by hyperlipidemia and the antioxidant activity. The aim of the study was to evaluate the effect of microalga Spirulina platensis on hippocampus lipoperoxidation and lipid profile in rats with induced hypercholesterolemia during 60 days. The measurement of hippocampus lipoperoxidation did not demonstrate significant difference (p>0.05) when Spirulina platensis was added to hypercholesterolemic diet. The evaluation of lipid profile showed that the administration of the microalga in therapeutic and preventive ways led to a significant protective effect (p<0.05) from hypercholesterolemia.

Show full item record


Files in this item

This item appears in the following Collection(s)


  • EQA - Artigos Publicados em Periódicos