Browsing ICB - Instituto de Ciências Biológicas by Author "Capella, Marcia Alves Marques"
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Methylene blue reverts multidrug resistance: sensitivity of multidrug resistant cells to this dye and its photodynamic action
Trindade, Gilma Santos; Farias, Shirley Leite de Almeida; Rumjanek, Vivian Mary Barral Dodd; Capella, Marcia Alves Marques (2000)Photodynamic action has been advocated as an alternative treatment of tumors but the most common used dyes, hematoporphyrin derivatives, are substrate for P-glycoprotein. This study investigated the MDR-reverting properties ... -
Sensitivity to microcystins: a comparative study in human cell lines with and without multidrug resistance phenotype
Votto, Ana Paula de Souza; Renon, Viviane Plasse; Yunes, João Sarkis; Rumjanek, Vivian Mary Barral Dodd; Capella, Marcia Alves Marques; Moura Neto, Vivaldo; Freitas, Marta Sampaio de; Monserrat, Laura Alicia Geracitano; Monserrat, José María; Trindade, Gilma Santos (2007)Multidrug resistance (MDR) is an obstacle in cancer treatment. An understanding of how tumoral cells react to oxidants can help us elucidate the cellular mechanism involved in resistance. Microcystins are cyanobacteria ...