Show simple item record Correia, Tiago Gabriel Narcizo, Amanda de Moraes Bianchini, Adalto Moreira, Renata Guimarães 2011-06-01T19:37:32Z 2011-06-01T19:37:32Z 2010
dc.identifier.citation CORREIA, Tiago Gabriel et al. Aluminum as an endocrine disruptor in female Nile tilapia (Oreochromis niloticus). Comparative Biochemistry and Physiology. C. Toxicology & Pharmacology, v. 151, p. 461-466, 2010. Disponível em: <>. Acesso em: 26 maio 2011. pt_BR
dc.identifier.issn 1532-0456
dc.description.abstract The effects of aluminum on plasma ion, lipid, protein and steroid hormone concentration were evaluated in Oreochromis niloticus broodstock females. Lipid and protein concentrations from the gonads and liver were also measured. Experiments were performed at neutral and acidicwater pH. Four groups of fish were tested for 96 h: 1) control conditions at neutral water pH; 2) control conditions at acidic water pH (CTR-Ac); 3) aluminum at neutral water pH (Al-N); and 4) aluminumat acidic water pH (Al-Ac). Aluminumand acidicwater pH exposure caused no ionoregulatory disturbances. Total lipid concentration increased inthemature gonads and decreased in the liver, suggesting an acceleration of lipid mobilization to the ovaries in animals exposed to aluminum. However, a decreased protein concentration in ovarieswas also observed. Exposure of control fish to acidicwater pH caused an increased concentration of plasma 17α-hydroxyprogesterone. However, females exposed to aluminum at acidic water pH showed a decreased of plasma 17α-hydroxyprogesterone and cortisol. No differences in plasma 17β-estradiol were observed. The physiological mechanisms underlying the disturbances observed are discussed focusing on reproduction. We suggest that aluminum can be considered an endocrine disrupting compound in mature O. niloticus females. pt_BR
dc.language.iso eng pt_BR
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dc.subject Aluminum pt_BR
dc.subject Cortisol pt_BR
dc.subject 17β-estradiol pt_BR
dc.subject 17α-hydroxyprogesterone pt_BR
dc.subject Plasma ions pt_BR
dc.subject PH pt_BR
dc.subject Proteins pt_BR
dc.subject Lipids pt_BR
dc.title Aluminum as an endocrine disruptor in female Nile tilapia (Oreochromis niloticus) pt_BR
dc.type article pt_BR

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