Microcystins (MCs) are toxins produced by cyanobacteria (blue-green algae), primarily Microcystis aeruginosa, forming water blooms worldwide. When an organism is exposed to environmental perturbations, alterations in normal ...

Background: The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu1 ] microcystin-LR. Methods: The antimicrobial ...

Microcystins are hepatotoxins suspected to generate oxidative stress. This mechanism was evaluated in gills of the estuarine crab Chasmagnathus granulatus (Decapoda, Brachyura). Adult male crabswere fed ground beef with ...

Antioxidant responses and oxidative stress were evaluated in the hepatopancreas of the estuarine crab Chasmagnathus granulates (Decapoda, Brachyura) after oral microcystin administration. Responses were evaluated through ...

A demanda alimentícia atual tem feito com que cultivos de organismos aquáticos se intensifiquem nas ultimas 3 décadas. Porém, para que isso seja possível fazendas de aquicultura tem aumentado o enriquecimento de seus ...

Background: Blooms of the saxitoxin-producing cyanobacterium Cylindrospermopsis raciborskii have been contaminating drinking water reservoirs in Brazil for many years. Although acute effects of saxitoxin intoxication are ...

Microcystins are usually the predominant cyanotoxins present in both drinking and recreational waters after cyanobacterial blooms. Their classic toxic effect is hepatotoxicity through inhibition of serine/threonine ...

Background: Toxic cyanobacterial blooms are recurrent in Patos Lagoon, in southern Brazil. Among cyanotoxins, [D-Leu1 ] microcystin-LR is the predominant variant whose natural cycle involves water and sediment ...

Biological degradation of cyanobacterial hepatotoxin microcystins in estuarine and coastal water samples from the Patos Lagoon estuarine system, a coastal lagoon situated at the southernmost region of Brazil, was observed. ...

This paper evaluated the chemoprotective effect of lipoic acid (LA) against microcystin (MC) toxicity in carp Cyprinus carpio. To determine the LA dose and the time necessary for the induction of three different classes ...

Florações de cianobactérias nocivas ocorrem frequentemente em reservatórios brasileiros, devido ao incremento de nutrientes pela eutrofização e pelas mudanças climáticas, como o aquecimento global. Estas florações alteram ...

Background: Many important toxins and antibiotics are produced by non-ribosomal biosynthetic pathways. Microcystins are a chemically diverse family of potent peptide toxins and the end-products of a hybrid NRPS and PKS ...

In January of 2003, a cyanobacterial bloom in the Patos Lagoon (Southern Brazil) (32 050S–52 120W) was observed. Water samples were taken to identify the composition and abundance of the bloom, as well as the occurrence ...

[D-Leu1]Microcystin-LR was identi®ed as the most abundant microcystin from a laboratory strain of the cyanobacterium Microcystis sp. isolated from a hepatotoxic Microcystis bloom from brackish waters in the Patos Lagoon ...

The effects of temperature and pH during extraction of toxin(s) from the cyanobacterial genus Anabaena were studied. Different extracts were compared for their anticholinesterase potency against purified eel acetylcholinesterase. ...

The objective of this work was to evaluate mechanisms of microcystin toxicity on crustacean species. Adult male crabs of Chasmagnathus granulatus (13.97"0.35 g) acclimated to low salinity (2‰) were injected with saline ...

The objective of this work was to evaluate mechanisms of microcystin toxicity on crustacean species. Adult male crabs of Chasmagnathus granulatus (13.97"0.35 g) acclimated to low salinity (2‰) were injected with saline ...

The effects of aqueous extracts from a cyanobacteria species, Anabaena spiroides, on fish (Odontesthes argentinensis), crab (Callinectes sapidus), and purified eel acetylcholinesterase (AChE) activity were studied. In vitro ...

Microcystins produced by cyanobacteria are potent inhibitors of some protein phosphatases, but recent evidence also indicatests potential to generate oxidative stress. In the present study, the effects of microcystin raw ...

As cianobactérias são organismos autotróficos comuns em diversos tipos de habitats naturais. Quando expostas à águas ricas em nutrientes, temperatura elevada e luz solar, podem formar florações. Essas florações podem afetar ...