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Kist, Luiza Wilges; Piato, Angelo Luis; Rosa, João Gabriel Santos da; Koakoski, Gessi; Barcellos, Leonardo José Gil; Yunes, João Sarkis; Bonan, Carla Denise; Bogo, Maurício Reis
(2011)
Microcystins (MCs) are toxins produced by cyanobacteria (blue-green algae), primarily Microcystis aeruginosa, forming water blooms worldwide. When an organism is exposed to environmental perturbations, alterations in normal ...
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Soares, Daniela Fernandes Ramos; Matthiensen, Alexandre; Colvara, Wilson Alves; Votto, Ana Paula de Souza; Trindade, Gilma Santos; Silva, Pedro Eduardo Almeida da; Yunes, João Sarkis
(2015)
Background: The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis
aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu1
] microcystin-LR.
Methods: The antimicrobial ...
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Lemes, Gilmar Antonio Farias; Kist, Luiza Wilges; Bogo, Maurício Reis; Yunes, João Sarkis
(2015)
Background: Toxic cyanobacterial blooms are recurrent in Patos Lagoon, in southern Brazil. Among cyanotoxins,
[D-Leu1
] microcystin-LR is the predominant variant whose natural cycle involves water and sediment ...
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Lemes, Gilmar Antonio Farias; Kersanach, Ralf; Pinto, Luciano da Silva; Dellagostin, Odir Antonio; Yunes, João Sarkis; Matthiensen, Alexandre
(2008)
Biological degradation of cyanobacterial hepatotoxin microcystins in estuarine and coastal water samples from the Patos Lagoon
estuarine system, a coastal lagoon situated at the southernmost region of Brazil, was observed. ...
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Amado, Lílian Lund; Garcia, Márcia Longaray; Pereira, Talita Carneiro Brandão; Yunes, João Sarkis; Bogo, Maurício Reis; Monserrat, José María
(2011)
This paper evaluated the chemoprotective effect of lipoic acid (LA) against microcystin (MC) toxicity in carp Cyprinus carpio. To determine the LA dose and the time necessary for the induction of three different classes ...
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Shishido, Tânia Keiko; Kaasalainen, Ulla; Fewer, David; Rouhiainen, Leo; Jokela, Jouni; Wahlsten, Matti; Fiore, Marli Fátima; Yunes, João Sarkis; Rikkinen, Jouko; Sivonen, Kaarina
(2013)
Background: Many important toxins and antibiotics are produced by non-ribosomal biosynthetic pathways.
Microcystins are a chemically diverse family of potent peptide toxins and the end-products of a hybrid NRPS and
PKS ...
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Matthiensen, Alexandre; Beattie, Kenneth A.; Yunes, João Sarkis; Kunimitsu, Kaya; Codd, Geoffrey
(2000)
[D-Leu1]Microcystin-LR was identi®ed as the most abundant microcystin from a laboratory strain of the cyanobacterium Microcystis sp. isolated from a hepatotoxic Microcystis bloom from brackish waters in the Patos Lagoon ...
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Barros, Lélia Pacheco Corrêia; Monserrat, José María; Yunes, João Sarkis
(2004)
The effects of temperature and pH during extraction of toxin(s) from the cyanobacterial genus Anabaena were studied.
Different extracts were compared for their anticholinesterase potency against purified eel acetylcholinesterase. ...
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Montserrat, José Maria; Yunes, João Sarkis; Bianchini, Adalto
(2001)
The effects of aqueous extracts from a cyanobacteria species, Anabaena spiroides, on fish (Odontesthes argentinensis), crab (Callinectes sapidus), and purified eel acetylcholinesterase (AChE) activity were studied. In vitro ...
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Gonçalves-Soares, Daniela; Zanette, Juliano; Yunes, João Sarkis; Yepiz-Plascencia, Glória; Bainy, Afonso Celso Dias
(2012)
Microcystin (MC) produced during cyanobacteria blooms is notably toxic to human and wildlife. Conjugation with reduced glutathione (GSH) by glutathione S transferase (GST) and the antioxidant enzymes defenses (e.g. catalase, ...
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Yunes, João Sarkis
(2009)
Florações da cianobactéria Microcystis são regulares e recorrentes na lagoa dos Patos e seu estuário (RS). Embora o primeiro registro científico seja datado de 1987, informações de antigos moradores das margens indicam que ...
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Amado, Lílian Lund; Garcia, Márcia Longaray; Ramos, Patrícia Baptista; Yunes, João Sarkis; Monserrat, José María
(2011)
We evaluated the effects of aqueous extracts of the cyanobacterium-producing microcystin (MC), Microcystis aeruginosa (strain ST9501), on detoxification capacity and glutathione (GSH) synthesis in liver, brain,
gill, and ...
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Lobo, Felipe de Lucia; Barbosa, Cláudio Clemente Faria; Novo, Evlyn Márcia Leão de Moraes; Yunes, João Sarkis
(2009)
This paper proposes an approach for using remote sensing data for identification and
mapping of cyanobacterial blooms; Methods: It uses two sets of spectra (empirical and theoretical) as reference to classify the areas ...
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Kist, Luiza Wilges; Fritsch, Rachel Seemann; Yunes, João Sarkis; Bonan, Carla Denise; Bogo, Maurício Reis
(2012)
Microcystins (MCs) are toxins produced by
cyanobacteria during the blooms that could
accumulate in aquatic animals and be relocated
to higher trophic levels. Adenosine triphosphate
(ATP) acts as an excitatory ...
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Leão, Janaina de Castro; Giordano, Sheila Bueno; Yunes, João Sarkis
(2010)
Microcystins (MCYST), common cyanobacterial hepatotoxins, have been observed in the Patos Lagoon and the estuary over the last three decades. Anthropogenic pollution associated to the environmental features has promoted ...
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Becker, Vanessa; Ihara, Priscilla Mieko; Yunes, João Sarkis; Huszar, Vera Lúcia de Moraes
(2010)
Cyanobacterial blooms and the accompanying
production of cyanotoxins are a serious global problem. Toxic blooms of Anabaena species are common in lagoons and reservoirs of southern Brazil. Worldwide, species of the
genus ...
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Ferreira, Ana Helena Ferreira; Minillo, Alessandro; Silva, Luciano de Mello; Yunes, João Sarkis
(2004)
O presente trabalho visou o estudo de Anabaena spiroides na Lagoa dos Patos e dos fatores ambientais favoráveis ao seu aparecimento. Durante 15 meses e em cinco pontos de amostragem ao longo do estuário, foram medidos ...
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Chaves, Priscila Freitas; Rocha, Sabrina de la; Dutra, Amanda; Yunes, João Sarkis
(2009)
Cianobactérias são microorganismos procariontes e autotróficos encontrados em diversos habitats. A disponibilidade de nitrogênio e fósforo e de condições ideais de temperatura e de pH nas águas favorecem as florações. No ...
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Ramos, Patricia Baptista; Diehl, Felipe; Santos, Juliane Marques dos; Monserrat, José María; Yunes, João Sarkis
(2014)
Saxitoxins (STXs) are neurotoxins produced by cyanobacteria such as Cylindrospermopsis raciborskii.
During bloom events, the production of these compounds causes contamination on public water supply
sources. STXs block ...
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Yunes, João Sarkis; Rocha, Sabrina de la; Giroldo, Danilo; Silveira, Savênia Bonoto da; Comin, Rubens; Bicho, Mirian da Silva; Melcher, Silvia Susanne; Sant'anna, Célia Leite; Vieira, Armando Augusto Henriques
(2009)
Raphidiopsis brookii P. J. Hil(cyanobacteria) was isolated from a small subtropical eutrophic pond (Biguá Pond) located in the grounds of Rio Grande University in the extreme south of Brazil, following a toxic bloom of ...